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07.16.2010 · Posted in Diseases & Conditions
Endometriosis - Definition, Causes, Symptoms and Treatment

 

Endometriosis (pronounced “en-doh-mee-tree-oh-sis”) is where cells like the ones found in the womb lining (endometrium) grow on organs outside the womb. These go through the same monthly changes as the womb lining itself, sometimes swelling and bleeding into the body cavity. This bleeding can cause pain and swelling because, unlike a normal monthly period, the blood from endometriosis can’t escape from the body through the vagina. Instead, the blood stays inside the body and may form rubbery bands of scar tissue, called adhesions. These can attach organs and tissues together and affect organs surrounding the womb.

Causes of Endometriosis

No one knows for sure what causes this disease. One theory is that during menstruation some of the menstrual tissue backs up through the fallopian tubes into the abdomen, where it implants and grows. Another theory suggests that endometriosis may be genetic, or runs in families.

Researchers also are looking at the role of the immune system and how it either stimulates or reacts to endometriosis. It may be that a woman’s immune system does not remove the menstrual fluid in the pelvic cavity properly, or the chemicals made by areas of endometriosis may irritate or promote growth of more areas. Results from a recent study showed that women who have the disease are more likely than other women to have immune system disorders in which the body attacks its own tissues. This study also found that women with endometriosis are more likely to have chronic fatigue syndrome and to suffer from fibromyalgia syndrome-a disease involving pain in the muscles, tendons, and ligaments.

Symptoms of endometriosis

Endometriosis is not an easy diagnosis to make. Symptoms such as chronic pelvic pain, menstrual pain, bloating, painful sex, or pelvic discomfort between ovulation and your period do heighten the index of suspicion, but aren’t conclusive. Notably, some women have the condition without symptoms, while others have these symptoms but no endometriosis. An experienced practitioner can tell much from a pelvic exam, but the only definitive diagnosis is surgical. This is another reason we recommend a natural approach as a first step to see if it provides symptom relief.

The cause of endometriosis is not known, although there are several theories. It’s possible that more than one theory is correct, and there are probably multiple pathways to developing the condition. One very likely contributing factor that can be reduced with natural methods is the estrogen-like chemicals that surround us, known as xenoestrogens.

The signs and symptoms of endometriosis include painful menses, pain with sexual intercourse, lower back or abdominal pain, sterility and constipation. In advanced cases of endometriosis, pain of the bladder, kidneys and bowel may become evident as well.

Treatment of Endometriosis

Treatment depends on the how bad the symptoms are, the severity of the disease, the woman’s desire to have children in the future, and her age.

Some women with mild disease and symptoms may just be monitored. It is important to maintain a regular schedule of examinations (every 6 to 12 months) to note any changes or to see if the disease has gotten worse.

Stopping the menstrual cycle creates a state resembling pregnancy (pseudopregnancy) and can help prevent the disease from getting worse. Pseudopregnancy can be created using oral contraceptives containing estrogen and progesterone. Women take the medicine consistently for 6 to 9 months. This type of therapy relieves most of the symptoms, but does not prevent scarring from the disease. Side effects include spotting of blood.

Watch video related to endometriosis treatment


Dr. Camran Nezhat, a gynecologic surgeon at El Camino Hospital, discusses endometriosis and the new, minimally invasive treatment options for this often misdiagnosed disease, which is a major cause of infertility in women.

Help answer the question about endometriosis treatment

What is the best treatment for Endometriosis?
My physician wants to give me Alesse (combo birth control). I am worried about the side effects, which are acne, excess hair, dark patches above lip and on forehead, WHICH I ALREADY HAVE!!! Including the occasional several pain from my right ovary.

I don't trust these doctors. They couldn't even find a reason for my chronic bronchitis so I'm seeing a specialist.

Please help me! Should I try the birth control? Is there another option?

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2 Responses to “Endometriosis – Definition, Causes, Symptoms and Treatment”

  1. This is an option I am considering for myself, and most insurances are covering it since it's non-invasive and non-surgical.

    Check out http://www.daretowearwhite.com

  2. Lupron Depot (leuprolide acetate for depot suspension) is a GnRH agonist — a hormone that works in two distinct phases. Phase one stimulates the ovaries causing them to produce more of the most potent of the three estrogens produced by women — estradiol. In phase two the messenger hormones that tell the ovaries to produce estrogen decline dramatically. This causes a significant reduction in estrogen levels, and causes women to experience menopause-like side effects.
    Lupron is prescribed for women with very bad endometriosis, severe menorrhagia, and before assisted reproduction. In men, Lupron is used to treat advanced prostate cancer, and the drug is used in children who are diagnosed with central precocious puberty (early puberty). Before you decide to use Lupron, make sure you understand the facts about the benefits and side effects so that you can make an informed decision.

    Side Effects and Lupron Depot
    Side effects that have been associated with the use of Lupron Depot frequently include hot flashes and night sweats, and less frequently palpitations, syncope, and tachycardias. Other side effects include generalized pain, headaches, vaginitis, nausea/vomiting, fluid retention[, weight gain, acne, hirsutism, joint pain, loss of sexual desire, depression, dizziness, nervousness, and breast changes such as tenderness and pain. There have been no deaths directly related to therapy with Lupron Depot.

    Lupron is an effective and medically accepted treatment for endometriosis. Despite the fact that many women do experience side effects during treatment with Lupron Depot, women often consider these side effects to be a necessary price to pay for the relief of the severe pain and suffering of endometriosis.

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